Strengths and limitations of commercial tests for hepatitis C virus RNA quantification.

نویسندگان

  • Chihiro Morishima
  • Minjun Chung
  • Ka Wing Ng
  • Donald J Brambilla
  • David R Gretch
چکیده

The sensitivity of the Roche COBAS Monitor v.2.0 test was slightly better than that of the Bayer bDNA 3.0 test, but the Monitor test underquantified specimens by 2.5- to 10.6-fold even at relatively low hepatitis C virus RNA concentrations. Dilution prior to assay minimally decreased the reproducibility of the Monitor assay, leading to the recommendation for all specimens to be diluted 1:100 prior to testing by this assay.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 42 1  شماره 

صفحات  -

تاریخ انتشار 2004